DR HAB. BOGNA RUDOLF, PROF. UŁ

Education:

• 2011 - Habilitation in Organic Chemistry "Metallocarbonyl complexes - synthesis, reactivity and attempts of application of selected complexes in biochemistry", University of Lodz.
• 1998 - Ph.D. in Organic Chemistry "CpFe(CO)2(η1-N- maleimide) and its derivatives as labels of biomolecules", supervisor prof. Janusz Zakrzewski, University of Lodz.
• 1998 - Master of Art in History of Art, University of Lodz.
• 1994 - Master of Science in Organic Chemistry, University of Lodz.

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Current position:

• since 2011 Associate prfessor, University of Lodz
• since 2014 Head of Department of Organic Chemistry, Faculty of Chemistry, University of Lodz
• since 2016 vice-Dean of Faculty of Chemistry for International Relations and Programs

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Group members:

• Dr Aneta Kosińska
• Dr Szymon Jarzyński
• Dr Sujoy Das (post-doc
• Agnieszka Łaska-Jesionowska (PhD Student
• Karolina Koprowska (PhD Student

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Research Fields:

• Organometallic Chemistry. Transition metallo-carbonyl complexes. Application of organometallic compounds in biochemistry as metallocarbonyl labels, enzyme inhibitors. Functionalization of nanoparticles and dendrimers with metallocarbonyl compounds. Click chemistry. Bioorthogonal reactions. Diels-Alder cycloaddition.

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Activities abroad:

•  1999-2000 CNRS, ICSN Gif-sur-Yvette-1 year, post-doc,
•  2003 Ecole Nationale Superieure de Chimie de Paris - 8 months, poste rouge
•  2005 Ecole Nationale Superieure de Chimie de Paris - 3 months, EMBO
•  2006 Ecole Nationale Superieure de Chimie de Paris - 3 months, EMBO
•  2008-2009 POLONIUM programme in cooperation with ENSCP
•  2010 Ecole Nationale Superieure de Chimie de Paris - 3 months, poste rouge
•  2014 SSHN BGF Ecole Nationale Superieure de Chimie de Paris, one month

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Current collaborations:

•  Dr hab. Michele Salmain, Ecole Nationale Superieure de Chimie de Paris
•  Prof. Jean-Luc Pirat ENSCM Montpellier France,
•  Dr hab. Agnieszka Wilczewska, Faculty of Chemistry, University of Bialystok
•  Dr hab. Emilia Fornal, Medical University of Lublin
•  Prof. dr hab. Katarzyna Woźniak, Faculty of Biology and Environmental Protection, University of Lodz
•  Dr hab. prof. MUL Paweł Szymański, Faculty of Pharmacy, Medical University of Lodz
•  Dr Sławomir Wojtulewski, Faculty of Chemistry, University of Bialystok

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Publications:

1. M. Salmain, N.Fischer-Durand, B. Rudolf
   "Bioorthogonal conjugation of transition organometallic complexes to peptides and proteins:strategies and applications", Eur.J.Chem.2020, 21-35.
2. D. Jamroz, N. Fischer-Durand, M. Palusiak, S. Wojtulewski, S. Jarzyński, M. Stępniewska, M.Salmain, B. Rudolf
   "Inverse electron-demand Diels-Alder (iEDDA) bioorthogonalconjugation of half-sandwich transitionmetallocarbonyl entities to a model protein", Appl Organometal Chem. 2020;e5507
3. N. Fischer‐Durand, D. Lizinska, V. Guérineau, B. Rudolf, M. Salmain
   "‘Clickable’ cyclopentadienyl iron carbonyl complexes for bioorthogonal conjugation of mid‐infrared labels to a model protein and PAMAM dendrimer",
   Appl Organometal Chem.2019;e4798
4. Wilczewska, A. Z.; Kosińska, A.; Misztalewska-Turkowicz, I.; Kubicka, A.; Niemirowicz-Laskowska, K.; Markiewicz, K. H.; Bucki, R.; Celichowski, G.; Kalska-Szostko, B.; Rudolf, B.
   "Magnetic Nanoparticles Bearing Metallocarbonyl Moiety as Antibacterial and Antifungal Agents."
   Applied Surface Science2019, 487, 601–609. DOI:10.1016/j.apsusc.2019.05.159.
5. D. Wysokiński, P. Lewandowska, D. Zątak, M. Juszczak, M. Kluska, D. Lizińska, B. Rudolf, K. Woźniak,
   "Photoactive CO-releasing complexes containing iron – genotoxicity and ability in HO-1 gene induction in HL-60 cells," Toxicol. Res., 2019, 8, 544
6. M. Salmain, N.Fischer-Durand, B. Rudolf
   "Bioorthogonal conjugation of transition organometallic complexes to peptides and proteins:strategies and applications", Eur.J.Chem. 2019, DOI: 10.1002/ejic.201900810
7. A. Kubicka, E. Parfieniuk, E. Fornal, M. Palusiak, D. Lizinska, A. Gumieniczek, B. Rudolf,
   "Metallocarbonyl complexes: (η5-C5H5)M(CO)n(η1-N-imidato) (M = Fe, Ru, Mo, W; n = 2, 3) as new photoactive CO-releasing molecules (CORMs) ",
   J. Photochem. Photobiol. A2018, 351, 115–123.
8. A. Kubicka, E. Fornal, A. Olejniczak, A. Rybarczyk-Pirek, S. Wojtulewski, B. Rudolf,
   "Oxa-Michael reaction of metallocarbonyl complexes bearing the maleimidato ligand. Reactivity studies with selected hydroxy compounds",
   Polyhedron2016, 107, 38–47.
9. B. Rudolf, M. Salmain, A. Kubicka, M. Palusiak, A. Rybarczyk-Pirek, S. Wojtulewski,
   "Synthesis and characterization of new M(II) carbonyl complexes (M = Fe or Ru) including an η1-N-maleimidato ligand. Reactivity studies with biological thiols".
   J. Organomet. Chem. (2016), 801, 101–110.
10. B. Rudolf, M. Salmain, A. Z. Wilczewska, A. Kubicka, I. Misztalewska, N. Fischer-Durand, "Fabrication of multifunctional magnetic nanoparticles bearing metallocarbonyl probes and antibodies",
    Colloids Surf. A, Physicochem. Eng. Aspects2014, 457, 142–151.
11. B. Rudolf, M. Salmain,, J. Grobelny, G. Celichowski, M. Cichomski,
    "Preparation of metallocarbonyl-gold-antibody bioconjugates for mid-IR optical immunosensing",
    J. Organomet. Chem. 2013, 734, 32–37.
12. B. Rudolf, M. Salmain, E. Fornal, A. Rybarczyk-Pirek,
    "Metallocarbonyl complexes of bromo- and dibromomaleimide: synthesis and biochemical application",
    Appl. Organometal. Chem. 2012, 26, 80–85.
13. B. Rudolf, M. Salmain, J. Grobelny, G. Celichowski, E. Tomaszewska,
    "Synthesis and characterization of metallocarbonyl functionalized gold nanoparticles",
    Colloids Surf. A.2011, 385, (1-3), 241–248.